• Overview
  • About Us
  • CVRM Pharmacology
  • R&D Enterprise
  • Contact
  • More
    • Overview
    • About Us
    • CVRM Pharmacology
    • R&D Enterprise
    • Contact
  • Overview
  • About Us
  • CVRM Pharmacology
  • R&D Enterprise
  • Contact

Gateway Preclinical Solutions, LLC

Cardiovascular Pharmacology

We apply our expertise in Heart, Renal, Hepatic, Metabolic and Co-morbid disease to design and execute comprehensive in vivo pharmacology strategies that generate the high-quality data needed to select the most promising lead candidates. We also develop translational data packages that connect preclinical findings to clinical strategy, informing trial design, biomarker selection, dose rationale, and patient stratification to improve the likelihood of clinical success.

Transforming Ideas into Assets

Confidence in Rationale

Confidence in Translation

Confidence in Translation

Assessment of Novel Therapeutic Targets and Pathways for Drug Development

Confidence in Translation

Confidence in Translation

Confidence in Translation

Selection of Predictive and Clinically Relevant Disease Models for Human Translatable Results

Candidate Selection

Confidence in Translation

Candidate Selection

Define Profile, Design Testing Scheme and Integrated Data Compilation

Proof of Mechanism

Proof of Mechanism

Candidate Selection

Elucidation of Mechanistic Pharmacology to Confirm Target Engagement and Biological Response

Study Management

Proof of Mechanism

Study Management

Full Lifecycle Support covering Design, Monitoring, Study Interpretation and Documentation

CRO Management

Proof of Mechanism

Study Management

Strategic Vendor Selection, Price Negotiation and Oversight to ensure Milestone Delivery

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